3-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine → HCID 66913454, compound

HRID 2104781Notes

Reaction equation

HRID 2104781 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:27])[F:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C[O:30][C:31](=[O:40])[CH2:32][C:33]1[CH:37]=[CH:36][S:35][C:34]=1[CH:38]=O>>[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH:24][CH2:38][C:34]3[S:35][CH:36]=[CH:37][C:33]=3[CH2:32][C:31]([OH:40])=[O:30])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:26])[F:27])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 112342973-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamineHCID 86598780HCID 86598780, compound

Product 1

HCID 66913454HCID 66913454, compound

Procedure

The title compound was prepared from {3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine and (2-formyl-thiophen-3-yl)-acetic acid methyl ester according to the procedure of Example 66. MS (ES) m/z 531.1.

Sources & evidence

ORD record
ord-64b20155f6094a529f885647f019c612
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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