3-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine → HCID 66914205, compound

HRID 2104784Notes

Reaction equation

HRID 2104784 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:27])[F:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:29][C:30]1[CH:35]=[CH:34][C:33]([C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=2)=[CH:32][C:31]=1[CH:42]=O>>[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH:24][CH2:42][C:31]3[CH:32]=[C:33]([C:36]4[CH:37]=[CH:38][CH:39]=[CH:40][CH:41]=4)[CH:34]=[CH:35][C:30]=3[F:29])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:26])[F:27])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 112342973-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamineHCID 167685234-Fluoro[1,1'-biphenyl]-3-carbaldehyde

Product 1

HCID 66914205HCID 66914205, compound

Procedure

The title compound was prepared from {3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine and 4-fluoro-biphenyl-3-carbaldehyde according to the procedure of Example 66. MS (ES) m/z 563.0.

Sources & evidence

ORD record
ord-9592b31721394beda52b6716580132a4
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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