3-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine → HCID 66914054, compound

HRID 2104785Notes

Reaction equation

HRID 2104785 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:27])[F:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:29][C:30]1[CH:31]=[C:32]([C:38]2[CH:43]=[CH:42][C:41]([O:44][CH3:45])=[CH:40][CH:39]=2)[CH:33]=[CH:34][C:35]=1[CH:36]=O>>[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH:24][CH2:36][C:35]3[CH:34]=[CH:33][C:32]([C:38]4[CH:43]=[CH:42][C:41]([O:44][CH3:45])=[CH:40][CH:39]=4)=[CH:31][C:30]=3[F:29])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:26])[F:27])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 112342973-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamineHCID 23005036HCID 23005036, compound

Product 1

HCID 66914054HCID 66914054, compound

Procedure

The title compound was prepared from {3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine and 3-fluoro-4′-methoxy-biphenyl-4-carbaldehyde according to the procedure of Example 66. MS (ESI) m/z 593.

Sources & evidence

ORD record
ord-fdd11043825a4cb8af78adbfd29caeca
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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