1-Acetyl-1H-indole-3-carbaldehyde → HCID 66914596, compound

HRID 2104789Notes

Reaction equation

HRID 2104789 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:27])[F:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:29]([N:32]1[C:40]2[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=2)[C:34]([CH:41]=O)=[CH:33]1)(=[O:31])[CH3:30]>>[C:29]([N:32]1[C:40]2[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=2)[C:34]([CH2:41][NH:24][C:20]2[CH:21]=[CH:22][CH:23]=[C:18]([C:17]3[C:16]4[C:11](=[C:12]([C:25]([F:28])([F:26])[F:27])[CH:13]=[CH:14][CH:15]=4)[N:10]=[CH:9][C:8]=3[CH2:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)[CH:19]=2)=[CH:33]1)(=[O:31])[CH3:30]

Participants

3

Reactant 2

HCID 899151-Acetyl-1H-indole-3-carbaldehydeHCID 112342973-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine

Product 1

HCID 66914596HCID 66914596, compound

Procedure

The title compound was prepared from {3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine and 1-acetyl-1H-indole-3-carbaldehyde according to the procedure of Example 66. MS (ES) m/z 550.0.

Sources & evidence

ORD record
ord-f3bf0da1bb0a4dfc8d44766e36141893
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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