3-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine → HCID 66913688, compound

HRID 2104791Notes

Reaction equation

HRID 2104791 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:27])[F:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(NC([N:36]1[CH:40]=[CH:39][CH:38]=[C:37]1[C:41]1[CH:46]=[CH:45][C:44]([F:47])=[C:43]([CH:48]=O)[CH:42]=1)=O)(C)(C)C>>[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH:24][CH2:48][C:43]3[CH:42]=[C:41]([C:37]4[NH:36][CH:40]=[CH:39][CH:38]=4)[CH:46]=[CH:45][C:44]=3[F:47])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:26])[F:27])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 112342973-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamineHCID 86598784HCID 86598784, compound

Product 1

HCID 66913688HCID 66913688, compound

Procedure

The title compound was prepared from {3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine and 2-(4-fluoro-3-formyl-phenyl)-pyrrole-1-carboxylic acid tert-butylamide according to the procedure of Example 66. MS (ES) m/z 552.0;

Sources & evidence

ORD record
ord-3b5b54fd50a94e33ab6167b92bc77391
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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