3-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine → HCID 66913939, compound
Reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:27])[F:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C[O:30][C:31](=[O:47])[CH2:32][C:33]1[CH:34]=[C:35]([C:39]2[CH:44]=[CH:43][C:42]([CH:45]=O)=[CH:41][CH:40]=2)[CH:36]=[CH:37][CH:38]=1>>[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH:24][CH2:45][C:42]3[CH:43]=[CH:44][C:39]([C:35]4[CH:36]=[CH:37][CH:38]=[C:33]([CH2:32][C:31]([OH:47])=[O:30])[CH:34]=4)=[CH:40][CH:41]=3)[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:26])[F:27])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
This compound was prepared according to the procedure of example 66, substituting 3-(3-benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine and (4′-formyl-biphenyl-3-yl)-acetic acid methyl ester. MS (ESI) m/z 601.
Workup
- customThis compound was prepared
Sources & evidence
- ORD record
- ord-b1285b47f7f44f8a92487d036289fe97
- Source dataset
- uspto-grants-2009_08
- Patent number
- US07576215B2
Reaction notes
Loading…