[4-(3-Aminophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone → HCID 66913786, compound

HRID 2104807Notes

Reaction equation

HRID 2104807 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:22]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:23])[CH:5]=[CH:6][CH:7]=1.C[O:31][C:32](=[O:48])[CH2:33][C:34]1[CH:35]=[C:36]([C:40]2[CH:45]=[CH:44][C:43]([CH:46]=O)=[CH:42][CH:41]=2)[CH:37]=[CH:38][CH:39]=1>>[C:22]([C:9]1[CH:10]=[N:11][C:12]2[C:17]([C:8]=1[C:4]1[CH:3]=[C:2]([NH:1][CH2:46][C:43]3[CH:44]=[CH:45][C:40]([C:36]4[CH:37]=[CH:38][CH:39]=[C:34]([CH2:33][C:32]([OH:48])=[O:31])[CH:35]=4)=[CH:41][CH:42]=3)[CH:7]=[CH:6][CH:5]=1)=[CH:16][CH:15]=[CH:14][C:13]=2[C:18]([F:21])([F:19])[F:20])(=[O:23])[C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1

Participants

3

Reactant 2

HCID 11326798[4-(3-Aminophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)MethanoneHCID 86598785HCID 86598785, compound

Product 1

HCID 66913786HCID 66913786, compound

Procedure

This compound was prepared according to the procedure of example 66, substituting [4-(3-amino-phenyl)-8-trifluoromethyl-quinolin-3-yl]-phenyl-methanone and (4′-formylbiphenyl-3-yl)-acetic acid methyl ester. MS (ESI) m/z 615.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-8997a39a9ec14bfe8e6164644b4422de
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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