3-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine → HCID 66914014, compound

HRID 2104808Notes

Reaction equation

HRID 2104808 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:27])[F:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C[O:30][C:31](=[O:47])[C:32]1[CH:37]=[CH:36][C:35]([N:38]2[CH2:43][CH2:42][CH:41]([CH2:44][CH:45]=O)[CH2:40][CH2:39]2)=[CH:34][CH:33]=1>>[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH:24][CH2:45][CH2:44][CH:41]3[CH2:42][CH2:43][N:38]([C:35]4[CH:34]=[CH:33][C:32]([C:31]([OH:47])=[O:30])=[CH:37][CH:36]=4)[CH2:39][CH2:40]3)[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:26])[F:27])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Procedure

This compound was prepared according to the procedure of example 66, substituting 3-(3-benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine and 4-[4-(2-oxo-ethyl)-piperidin-1-yl]-benzoic acid methyl ester. MS (ESI) m/z 610.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-d0484a216fae48da9451b60752fce342
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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