3-(3-(Trifluoromethyl)phenoxy)benzaldehyde → {3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}{3-[3-(Trifluoromethyl)Phenoxy]Benzyl}Amine

HRID 2104813Notes

Reaction equation

HRID 2104813 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:27])[F:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:29][C:30]([F:47])([F:46])[C:31]1[CH:32]=[C:33]([CH:43]=[CH:44][CH:45]=1)[O:34][C:35]1[CH:36]=[C:37]([CH:40]=[CH:41][CH:42]=1)[CH:38]=O>>[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH:24][CH2:38][C:37]3[CH:40]=[CH:41][CH:42]=[C:35]([O:34][C:33]4[CH:43]=[CH:44][CH:45]=[C:31]([C:30]([F:29])([F:46])[F:47])[CH:32]=4)[CH:36]=3)[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:26])[F:27])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 5227113-(3-(Trifluoromethyl)phenoxy)benzaldehydeHCID 112342973-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine

Product 1

HCID 86598787{3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}{3-[3-(Trifluoromethyl)Phenoxy]Benzyl}Amine

Procedure

This compound was prepared according to the procedure of example 66, substituting 3-(3-benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine and 3-(3-trifluoromethyl phenoxy)-benzaldehyde. MS (ESI) m/z 629.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-19871b771fc240378bcd98f5614a7206
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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