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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104859Generated: October 31, 2026

Loxoprofen Impurity 18 → HCID 66913788, compound

https://huagongshe.com/reaction/2104859

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLoxoprofen Impurity 18HCID 11242311—
Reactant3-(8-Chloro-3-methylquinolin-4-yl)phenolHCID 53411971—
ProductHCID 66913788HCID 66913788—

Reaction Steps

This compound was prepared according to the procedure of example 41, substituting 3-(8-chloro-3-methyl-quinolin-4-yl)-phenol and 2-(4-bromomethyl-phenyl)-propionic acid methyl ester. Purification by supercritical fluid chromatography (MeOH/CO2). Electronic circular dichroism CD λmax=+6 mdeg @ 226 nm (EtOH). MS (ESI) m/z 432.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-29b5d020b4f84b39887ed37dbc9126a6
Source noteuspto-grants-2009_08