2-(Propan-2-yloxy)benzaldehyde → {3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}(2-Isopropoxybenzyl)Amine

HRID 2104867Notes

Reaction equation

HRID 2104867 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:27])[F:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:29]([O:32][C:33]1[CH:40]=[CH:39][CH:38]=[CH:37][C:34]=1[CH:35]=O)([CH3:31])[CH3:30]>>[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH:24][CH2:35][C:34]3[CH:37]=[CH:38][CH:39]=[CH:40][C:33]=3[O:32][CH:29]([CH3:31])[CH3:30])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:26])[F:27])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 2500782-(Propan-2-yloxy)benzaldehydeHCID 112342973-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine

Product 1

HCID 66914485{3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}(2-Isopropoxybenzyl)Amine

Procedure

This compound was prepared according to the procedure of example 66, substituting 3-(3-benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine and 2-isopropoxy-benzaldehyde. MS (ESI) m/z 527.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-f565dd1f732f4b74a8f2f2eee0b13689
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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