2,4-Bis(trifluoromethyl)benzaldehyde → {3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}[2,4-Bis(Trifluoromethyl)Benzyl]Amine

HRID 2104869Notes

Reaction equation

HRID 2104869 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:27])[F:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:29][C:30]([F:44])([F:43])[C:31]1[CH:38]=[C:37]([C:39]([F:42])([F:41])[F:40])[CH:36]=[CH:35][C:32]=1[CH:33]=O>>[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH:24][CH2:33][C:32]3[CH:35]=[CH:36][C:37]([C:39]([F:42])([F:41])[F:40])=[CH:38][C:31]=3[C:30]([F:29])([F:43])[F:44])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:26])[F:27])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 27360952,4-Bis(trifluoromethyl)benzaldehydeHCID 112342973-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine

Product 1

HCID 86598797{3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}[2,4-Bis(Trifluoromethyl)Benzyl]Amine

Procedure

This compound was prepared according to the procedure of example 66, substituting 3-(3-benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine and 2,4-bis-trifluoromethyl-benzaldehyde. MS (ESI) m/z 602.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-3cb7d6e0657f48e09803ac2884ebb173
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

Loading…