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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104879Generated: October 30, 2026

2-(Trifluoromethoxy)benzyl alcohol → 3-Benzyl-4-(3-{[2-(Trifluoromethoxy)Benzyl]Oxy}Phenyl)-8-(Trifluoromethyl)Quinoline

https://huagongshe.com/reaction/2104879

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethoxy)benzyl alcoholHCID 2777245—
Reactant3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenolHCID 53630755—
Product3-Benzyl-4-(3-{[2-(Trifluoromethoxy)Benzyl]Oxy}Phenyl)-8-(Trifluoromethyl)QuinolineHCID 86598801—

Reaction Steps

This compound was prepared according to the procedure of example 69, substituting 3-(3-benzyl-8-trifluoromethyl-quinolin-4-yl)-phenol and (2-trifluoromethoxy-phenyl)-methanol. MS (ESI) m/z 554.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-92406c7ffed0450285bfdfeb2a692ff3
Source noteuspto-grants-2009_08