(3-hydroxyphenyl)boronic Acid → 3-(8-Chloro-3-methylquinolin-4-yl)phenol

HRID 2104886Notes

Reaction equation

HRID 2104886 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1Br)=[CH:15][CH:14]=[CH:13][C:12]=2[Cl:19])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH:20]C1C=C(B(O)O)C=CC=1>>[Cl:19][C:12]1[CH:13]=[CH:14][CH:15]=[C:16]2[C:11]=1[N:10]=[CH:9][C:8]([CH3:17])=[C:1]2[C:2]1[CH:3]=[C:4]([OH:20])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 2734359(3-hydroxyphenyl)boronic AcidHCID 66913851HCID 66913851, compound

Product 1

HCID 534119713-(8-Chloro-3-methylquinolin-4-yl)phenol

Procedure

The title compound was prepared from 3-benzyl-4-bromo-8-chloro-quinoline and 3-hydroxyphenyl boronic acid according to the procedure of Example 1. MS (ES) m/z 267.9.

Sources & evidence

ORD record
ord-8157535fdf9b426f89c1515d1df36390
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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