Diethanolamine → HCID 68815479, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of Intermediate 138.1 (30 mg, 0.124 mmol) and diethanolamine (32.6 mg, 0.31 mmol) in DMF (0.5 mL) was stirred at 130° C. for 5 h, then 140° C. for 15 h. The mixture was diluted with EtOAc, washed with water (2×) and brine, dried (Na2SO4), filtered through a 1″ pad of silica gel, then was concentrated. The crude residue was used in the following step without further purification.

Provenance & Evidence