Tetrabutylammonium Fluoride → HCID 68812543, compound

Participants

Reaction Steps

To a solution of Intermediate 191.1 (72 mg, 0.0936 mmol) in 1 mL THF at rt, was added TBAF (1 M in THF, 0.094 mL, 0.094 mmol). The mixture was stirred at rt for 30 min, then concentrated. The mixture was diluted with EtOAc, washed with H2O (2×) and brine, dried (Na2SO4) and concentrated. The crude product was purified by flash chromatography (0 to 75% EtOAc/hexanes gradient) to afford 42 mg of Intermediate 191.2 as a colorless residue.

Provenance & Evidence