1-(1,1-diethoxyethyl)-1H-pyrazole → HCID 178436485, compound

HRID 2105040Notes

Reaction equation

HRID 2105040 reaction equation
C(O[C:4]1[CH:5]=[C:6](OC(C)C)[C:7]([F:25])=[C:8]([N:10]([CH2:19][C:20]2[CH:24]=[CH:23][NH:22][N:21]=2)[C:11]2[CH:18]=[CH:17][C:14]([C:15]#[N:16])=[CH:13][CH:12]=2)[CH:9]=1)C.[CH2:30](C1C=CC(F)=C(C=1)C=CC1C=CC(C#N)=CC=1)[CH3:31].C(OC(N1C=CC=N1)(OCC)C)C>>[CH2:30]([C:4]1[CH:5]=[CH:6][C:7]([F:25])=[C:8]([N:10]([CH2:19][C:20]2[CH:24]=[CH:23][NH:22][N:21]=2)[C:11]2[CH:12]=[CH:13][C:14]([C:15]#[N:16])=[CH:17][CH:18]=2)[CH:9]=1)[CH3:31]

Participants

4

Reactant 3

HCID 688133781-(1,1-diethoxyethyl)-1H-pyrazoleHCID 688172594-(5-Ethyl-2-fluorostyryl)benzonitrileHCID 178467025HCID 178467025, compound

Product 1

HCID 178436485HCID 178436485, compound

Procedure

According to procedure for the preparation of Intermediate 183.1, reaction of Intermediate 262.1 with 1-(1,1-diethoxyethyl)-1H-pyrazole afforded Intermediate 264.1.

Sources & evidence

ORD record
ord-342f6105969c47b2b8353cd10745be3c
Source dataset
uspto-grants-2009_08
Patent number
US07576098B2

Reaction notes

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