참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1,2-Dichlorobenzene | HCID 7239 | — |
| 반응물 | 6-Bromohexanoic acid | HCID 20210 | — |
| 반응물 | 5-Methoxy-2,3,3-trimethyl-3H-indole | HCID 11095392 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 1-(5-carboxypentyl)-5-methoxy-2,3,3-trimethyl-3H-indolium bromide | HCID 68816685 | 80.9% |
반응 단계
To 5-methoxy-2,3,3-trimethyl-3H-indole (1.9 g) was added 6-bromohexanoic acid (3 g) and 1,2-dichlorobenzene (10 ml). The mixture was heated to 100° C. for 3 hours and then allowed to cool to room temperature. Diethyl ether was added and the precipitated material removed by filtration. Drying in a vacuum oven gave the product (3.12 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07579140B2 |
|---|
| 출처 데이터셋 | uspto-grants-2009_08 |
|---|
| ORD ID | ord-3854d7164f204f69a8ecac9545dc67fe |
|---|
| 출처 메모 | uspto-grants-2009_08 |
|---|
