HuagongsheHuagongshe Chemistry Print Report · For research reference only
Serinol → 2-[[(2,3-Difluorophenyl)methyl]thio]4-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-7(8H)-pteridinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Serinol | HCID 68294 | — |
| Reactant | 4-bromo-2-[[(2,3-difluorophenyl)methyl]thio]-7(8H)-pteridinone | HCID 22320082 | — |
| Product | 2-[[(2,3-Difluorophenyl)methyl]thio]4-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-7(8H)-pteridinone | HCID 22505978 | 69.4% |
Reaction Steps
The titled compound (57 mg) was prepared from the product of step (b) (80 mg) and 2-amino-1,3-propanediol (29 mg) using the method of Example 2 step (f).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579342B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-3c8a4ec7791e43c1aa2538cc98fe41fd |
| Source note | uspto-grants-2009_08 |