Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105157Generated: November 2, 2026

(1,2-Oxazol-5-yl)methanethiol → 4-[[(1R)-2-Hydroxy-1-methylethyl]amino]-2-[(5-isoxazolylmethyl)thio]-7(8H)-pteridinone

https://huagongshe.com/reaction/2105157

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,2-Oxazol-5-yl)methanethiolHCID 15646082—
Reactant2-[[(2,3-Difluorophenyl)methyl]sulfonyl]-4-[[(1R)-2-hydroxy-1-methylethyl]amino]-7(8H)-pteridinoneHCID 68817193—
Product4-[[(1R)-2-Hydroxy-1-methylethyl]amino]-2-[(5-isoxazolylmethyl)thio]-7(8H)-pteridinoneHCID 68815381—

Reaction Steps

The titled compound (0.038 g) was prepared by the method of Example 13, step (c) using the product from Example 13, step (a) (00.10 g) and 5-isoxazolylmethylmercaptan (0.057 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579342B2
Source datasetuspto-grants-2009_08
ORD IDord-e03ddded21954095a204da056b78c2ab
Source noteuspto-grants-2009_08