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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105161Generated: October 31, 2026

Thenyl mercaptan → 4-[[(1R)-2-Hydroxy-1-methylethyl]amino]-2-[[(2-thienyl)methyl)thio]-7(8H)-pteridinone

https://huagongshe.com/reaction/2105161

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThenyl mercaptanHCID 80408—
Reactant2-[[(2,3-Difluorophenyl)methyl]sulfonyl]-4-[[(1R)-2-hydroxy-1-methylethyl]amino]-7(8H)-pteridinoneHCID 68817193—
Product4-[[(1R)-2-Hydroxy-1-methylethyl]amino]-2-[[(2-thienyl)methyl)thio]-7(8H)-pteridinoneHCID 6881613456.6%

Reaction Steps

The titled compound (0.076 g) was prepared by the method of Example 13, step (c) using the product from Example 13, step (a) (0.20 g) and 2-thienylmethylmercaptan (0.050 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579342B2
Source datasetuspto-grants-2009_08
ORD IDord-7351a331112e499eb71703af752f1a2c
Source noteuspto-grants-2009_08