HCID 22505944, compound → HCID 68813203, compound

HRID 2105164Notes

Reaction equation

HRID 2105164 reaction equation

Br[C:2]1[C:11]2[N:10]=[C:9]([CH3:12])[C:8](=[O:13])[NH:7][C:6]=2[N:5]=[C:4]([S:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[C:17]=2[F:23])[N:3]=1>N[C@@H](CO)C>[F:23][C:17]1[C:18]([F:22])=[CH:19][CH:20]=[CH:21][C:16]=1[CH2:15][S:14][C:4]1[N:3]=[C:2]([NH:10][C@H:9]([CH3:12])[CH2:8][OH:13])[C:11]2[N:10]=[C:9]([CH3:12])[C:8](=[O:13])[NH:7][C:6]=2[N:5]=1

Participants

3

Reactant 1

HCID 22505944HCID 22505944, compound

Product 1

HCID 68813203HCID 68813203, compound

Reagents, catalysts & solvents 1

HCID 80308(R)-(-)-2-Amino-1-propanolSolvent

Procedure

The titled compound was prepared from the product of example 35, step (b) (2.00 mg) and D-alaninol (120 μl) using the method of Example 2, step (f).

Sources & evidence

ORD record: ord-c34d9f1fa919484baab559221a45cc65
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07579342B2

Reaction notes

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