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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105166Generated: October 30, 2026

Bromoform → 4-Bromo-2-[[(2,3-difluorophenyl)methyl]thio]-7,8-dihydro-7-oxo-6-pteridinecarboxylic Acid Ethyl Ester

https://huagongshe.com/reaction/2105166

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromoformHCID 5558—
Reactant4-Amino-2-[[(2,3-difluorophenyl)methyl]thio]-7,8-dihydro-7-oxo-6-pteridinecarboxylic Acid Ethyl EsterHCID 68816120—
Product4-Bromo-2-[[(2,3-difluorophenyl)methyl]thio]-7,8-dihydro-7-oxo-6-pteridinecarboxylic Acid Ethyl EsterHCID 86600021—

Reaction Steps

The sub-titled compound was prepared from the product of example 36, step (a) (2 g) and bromoform (40 ml) using the method of Example 3, step (b).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579342B2
Source datasetuspto-grants-2009_08
ORD IDord-fe2470b21a824c1f908d549f8bb399d1
Source noteuspto-grants-2009_08