HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105182Generated: November 1, 2026
Thionyl Chloride → Methyl 3-(chlorocarbonyl)benzoate
https://huagongshe.com/reaction/2105182
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 1,3-Benzenedicarboxylic acid, monomethyl ester | HCID 6951279 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | Methyl 3-(chlorocarbonyl)benzoate | HCID 15563901 | — |
Reaction Steps
SOCl2 (15 mL) and dry DMF (2 drops) were added to monomethyl isophthalate (5 g, 17.7 mmol), and the reaction mixture was refluxed at 80° C. for 6 hr. The SOCl2 was removed in vacuo, and a colorless oil was obtained and used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07579350B2 |
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| Source dataset | uspto-grants-2009_08 |
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| ORD ID | ord-f2d0974938cf4057a5d1b21a5cf35322 |
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| Source note | uspto-grants-2009_08 |
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