3-cyclopropyl-1H-pyrazol-5-amine → HCID 11371992, compound

HRID 2105188Notes

Reaction equation

HRID 2105188 reaction equation
O[C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([N:9]2[CH2:13][CH2:12][CH2:11][CH:10]2[C:14]2[O:18][N:17]=[C:16]([CH3:19])[CH:15]=2)[N:3]=1.[NH2:20][C:21]1[CH:25]=[C:24]([CH:26]2[CH2:28][CH2:27]2)[NH:23][N:22]=1>>[CH:26]1([C:24]2[NH:23][N:22]=[C:21]([NH:20][C:2]3[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([N:9]4[CH2:13][CH2:12][CH2:11][CH:10]4[C:14]4[O:18][N:17]=[C:16]([CH3:19])[CH:15]=4)[N:3]=3)[CH:25]=2)[CH2:28][CH2:27]1

Participants

3

Reactant 2

HCID 27580143-cyclopropyl-1H-pyrazol-5-amineHCID 178422717HCID 178422717, compound

Product 1

HCID 11371992HCID 11371992, compound

Procedure

Starting materials: 4-hydroxy-6-methyl-2-[2-{3-(methyl)isoxazol-5-yl}pyrrolidin-1-yl]pyrimidine (Method 31) and 3-amino-5-cyclopropyl-1H-pyrazole (Method 7 of WO-03/048133).

Sources & evidence

ORD record
ord-ca1a071d827f421cb3e4415dc609447f
Source dataset
uspto-grants-2009_08
Patent number
US07579349B2

Reaction notes

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