1H-Pyrazol-3-amine, 5-methyl- → HCID 11452763, compound

HRID 2105189Notes

Reaction equation

HRID 2105189 reaction equation
O[C:2]1[CH:7]=[C:6]([CH2:8][CH3:9])[N:5]=[C:4]([N:10]2[CH2:14][CH2:13][CH2:12][CH:11]2[C:15]2[O:19][N:18]=[C:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=3)[CH:16]=2)[N:3]=1.[NH2:26][C:27]1[CH:31]=[C:30]([CH3:32])[NH:29][N:28]=1>>[CH2:8]([C:6]1[N:5]=[C:4]([N:10]2[CH2:14][CH2:13][CH2:12][CH:11]2[C:15]2[O:19][N:18]=[C:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=3)[CH:16]=2)[N:3]=[C:2]([NH:26][C:27]2[CH:31]=[C:30]([CH3:32])[NH:29][N:28]=2)[CH:7]=1)[CH3:9]

Participants

3

Reactant 2

HCID 931461H-Pyrazol-3-amine, 5-methyl-HCID 178436952HCID 178436952, compound

Product 1

HCID 11452763HCID 11452763, compound

Procedure

Starting materials: 4-hydroxy-6-ethyl-2-[2-{3-(pyrid-2-yl)isoxazol-5-yl}pyrrolidin-1-yl]pyrimidine (Method 32) and 3-amino-5-methyl-1H-pyrazole.

Sources & evidence

ORD record
ord-d15ab70f38d74d78a5429211ae1856a6
Source dataset
uspto-grants-2009_08
Patent number
US07579349B2

Reaction notes

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