1H-Pyrazol-3-amine, 5-methyl- → HCID 11294137, compound

HRID 2105190Notes

Reaction equation

HRID 2105190 reaction equation
O[C:2]1[CH:7]=[C:6]([CH2:8][CH2:9][CH2:10][O:11][CH3:12])[N:5]=[C:4]([N:13]2[CH2:17][CH2:16][CH2:15][CH:14]2[C:18]2[O:22][N:21]=[C:20]([C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][N:24]=3)[CH:19]=2)[N:3]=1.[NH2:29][C:30]1[CH:34]=[C:33]([CH3:35])[NH:32][N:31]=1>>[CH3:12][O:11][CH2:10][CH2:9][CH2:8][C:6]1[N:5]=[C:4]([N:13]2[CH2:17][CH2:16][CH2:15][CH:14]2[C:18]2[O:22][N:21]=[C:20]([C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][N:24]=3)[CH:19]=2)[N:3]=[C:2]([NH:29][C:30]2[CH:34]=[C:33]([CH3:35])[NH:32][N:31]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 931461H-Pyrazol-3-amine, 5-methyl-HCID 178494892HCID 178494892, compound

Product 1

HCID 11294137HCID 11294137, compound

Procedure

Starting materials: 4-hydroxy-6-(3-methoxypropyl)-2-[2-{3-(pyrid-2-yl)isoxazol-5-yl}pyrrolidin-1-yl]pyrimidine (Method 33) and 3-amino-5-methyl-1H-pyrazole.

Sources & evidence

ORD record
ord-6aaf4fdc315a4b249c4135dc19e69746
Source dataset
uspto-grants-2009_08
Patent number
US07579349B2

Reaction notes

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