1H-Pyrazol-3-amine, 5-methyl- → HCID 11178126, compound

HRID 2105192Notes

Reaction equation

HRID 2105192 reaction equation
O[C:2]1[CH:7]=[C:6]([CH2:8][O:9][CH3:10])[N:5]=[C:4]([N:11]2[CH2:15][CH2:14][CH2:13][CH:12]2[C:16]2[O:20][N:19]=[C:18]([C:21]3[S:22][CH:23]=[CH:24][N:25]=3)[CH:17]=2)[N:3]=1.[NH2:26][C:27]1[CH:31]=[C:30]([CH3:32])[NH:29][N:28]=1>>[CH3:10][O:9][CH2:8][C:6]1[N:5]=[C:4]([N:11]2[CH2:15][CH2:14][CH2:13][CH:12]2[C:16]2[O:20][N:19]=[C:18]([C:21]3[S:22][CH:23]=[CH:24][N:25]=3)[CH:17]=2)[N:3]=[C:2]([NH:26][C:27]2[CH:31]=[C:30]([CH3:32])[NH:29][N:28]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 931461H-Pyrazol-3-amine, 5-methyl-HCID 178494557HCID 178494557, compound

Product 1

HCID 11178126HCID 11178126, compound

Procedure

Starting materials: 4-hydroxy-6-methoxymethyl-2-[2-{3-(thiazol-2-yl)isoxazol-5-yl}pyrrolidin-1-yl]pyrimidine (Method 36) and 3-amino-5-methyl-1H-pyrazole.

Sources & evidence

ORD record
ord-a01f094bc3e24ab2a88423d7a5fa5438
Source dataset
uspto-grants-2009_08
Patent number
US07579349B2

Reaction notes

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