1H-Pyrazol-3-amine, 5-methyl- → HCID 11177961, compound

HRID 2105193Notes

Reaction equation

HRID 2105193 reaction equation
O[C:2]1[CH:7]=[C:6]([CH2:8][O:9][CH3:10])[N:5]=[C:4]([N:11]2[CH2:15][CH2:14][CH2:13][CH:12]2[C:16]2[O:20][N:19]=[C:18]([C:21]3[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=3)[CH:17]=2)[N:3]=1.[NH2:27][C:28]1[CH:32]=[C:31]([CH3:33])[NH:30][N:29]=1>>[CH3:10][O:9][CH2:8][C:6]1[N:5]=[C:4]([N:11]2[CH2:15][CH2:14][CH2:13][CH:12]2[C:16]2[O:20][N:19]=[C:18]([C:21]3[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=3)[CH:17]=2)[N:3]=[C:2]([NH:27][C:28]2[CH:32]=[C:31]([CH3:33])[NH:30][N:29]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 931461H-Pyrazol-3-amine, 5-methyl-HCID 178494556HCID 178494556, compound

Product 1

HCID 11177961HCID 11177961, compound

Procedure

Starting materials: 4-hydroxy-6-methoxymethyl-2-[2-{3-(pyrid-3-yl)isoxazol-5-yl}pyrrolidin-1-yl]pyrimidine (Method 35(a)) and 3-amino-5-methyl-1H-pyrazole.

Sources & evidence

ORD record
ord-0f4c4b8498934591a40f35a8e1b9c0f5
Source dataset
uspto-grants-2009_08
Patent number
US07579349B2

Reaction notes

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