1H-Pyrazol-3-amine, 5-methyl- → HCID 11465241, compound

HRID 2105195Notes

Reaction equation

HRID 2105195 reaction equation
O[C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[N:5]=[C:4]([N:12]2[CH2:16][CH2:15][CH2:14][CH:13]2[C:17]2[O:21][N:20]=[C:19]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][N:23]=3)[CH:18]=2)[N:3]=1.[NH2:28][C:29]1[CH:33]=[C:32]([CH3:34])[NH:31][N:30]=1>>[CH3:34][C:32]1[NH:31][N:30]=[C:29]([NH:28][C:2]2[CH:7]=[C:6]([C:8]([F:9])([F:11])[F:10])[N:5]=[C:4]([N:12]3[CH2:16][CH2:15][CH2:14][CH:13]3[C:17]3[O:21][N:20]=[C:19]([C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][N:23]=4)[CH:18]=3)[N:3]=2)[CH:33]=1

Participants

3

Reactant 2

HCID 931461H-Pyrazol-3-amine, 5-methyl-HCID 178516144HCID 178516144, compound

Product 1

HCID 11465241HCID 11465241, compound

Procedure

Starting materials: 4-hydroxy-6-trifluoromethyl-2-[2-{3-(pyrid-2-yl)isoxazol-5-yl}pyrrolidin-1-yl]pyrimidine (Method 37) and 3-amino-5-methyl-1H-pyrazole.

Sources & evidence

ORD record
ord-2cb6311142fc45b1b9bfcc31a61197bd
Source dataset
uspto-grants-2009_08
Patent number
US07579349B2

Reaction notes

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