HRID2105344

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID95721

Ethyl 5-(phenylmethoxy)-1H-indole-2-carboxylate

C18H17NO3

HCID23665647

2-Methyl-2-propanol, potassium salt

C4H9KO

结构：C[C@@H]1CN(C(=O)OC(C)(C)C)S(=O)(=O)O1

HCID86612930

1,2,3-Oxathiazolidine-3-carboxylic acid, 5-methyl-, 1,1-dimethylethyl ester, 2,2-dioxide, (5R)-

C8H15NO5S

PRODUCTS

生成物

结构：CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2n1[C@@H](C)CNC(=O)OC(C)(C)C

HCID68462372

未命名化合物

收率 100%

PROCEDURE

实验过程

The title compound was synthesized in analogy to example 8, intermediate a), from ethyl 5-benzyloxyindole-2-carboxylate (commercially available), (R)-5-methyl-2,2-dioxo-[1,2,3]oxathiazolidine-3-carboxylic acid tert-butyl ester (prepared according to WO02/010169) and potassium tert-butoxide, to give the desired compound as a yellow solid (100%).