HRID2105348

反应详情

EQUATION

反应方程式

REACTANTS

反应物

反应SMILES：CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2[nH]1

HCID95721

Ethyl 5-(phenylmethoxy)-1H-indole-2-carboxylate

C18H17NO3

反应SMILES：C[C@H]1COS(=O)(=O)N1C(=O)OC(C)(C)C

HCID10988294

1,2,3-Oxathiazolidine-3-carboxylic acid, 4-methyl-, 1,1-dimethylethyl ester, 2,2-dioxide, (4S)-

C8H15NO5S

HCID23665647

2-Methyl-2-propanol, potassium salt

C4H9KO

PRODUCTS

产物

反应SMILES：CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2n1C[C@H](C)NC(=O)OC(C)(C)C

HCID68461704

未命名化合物

收率 100%

PROCEDURE

实验过程

The title compound was synthesized in analogy to example 1, intermediate b), from ethyl 5-benzyloxyindole-2-carboxylate (commercially available), (S)-4-methyl-2,2-dioxo-[1,2,3]oxathiazolidine-3-carboxylic acid tert-butyl ester (prepared according to WO02/010169) and potassium tert-butoxide, to give the desired compound as a light yellow solid (>100%). The so-obtained product was used in the next step without further purification.