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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105357Generated: November 2, 2026

Sodium hydride → HCID 16679705, compound

https://huagongshe.com/reaction/2105357

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium hydrideHCID 24758—
Reactant2-Bromoethyl methyl etherHCID 80972—
Reactant8-(1-isopropylpiperidin-4-yloxy)-3,4-dihydropyrazino[1,2-a]indol-1(2H)-oneHCID 16679518—
ProductHCID 16679705HCID 16679705—

Reaction Steps

The title compound was synthesized in analogy to example 17, from 8-(1-isopropyl-piperidin-4-yloxy)-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (example 1), sodium hydride and 2-bromoethyl methyl ether, to give the product as a white solid (28%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579351B2
Source datasetuspto-grants-2009_08
ORD IDord-0105f5c33bef4a3686461611a98a6955
Source noteuspto-grants-2009_08