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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105361Generated: November 3, 2026

2-Bromopropane → HCID 16678214, compound

https://huagongshe.com/reaction/2105361

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromopropaneHCID 6358—
ReactantSodium hydrideHCID 24758—
Reactant8-(1-isopropylpiperidin-4-yloxy)-3,4-dihydropyrazino[1,2-a]indol-1(2H)-oneHCID 16679518—
ProductHCID 16678214HCID 1667821410%

Reaction Steps

The title compound was synthesized in analogy to example 17, from 8-(1-isopropyl-piperidin-4-yloxy)-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (example 1), sodium hydride and 2-bromopropane, to give the desired product as white solid (10%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579351B2
Source datasetuspto-grants-2009_08
ORD IDord-d3b60ebd72194e098a200e4abd0dd7da
Source noteuspto-grants-2009_08