HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 46945057, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Bromomethylcyclopropane | HCID 81503 | — |
| Reactant | HCID 16679617 | HCID 16679617 | — |
| Product | HCID 46945057 | HCID 46945057 | — |
Reaction Steps
The title compound was synthesized in analogy to example 17, from (R)-8-(1-isopropyl-piperidin-4-yloxy)-3-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (example 14), 1-(bromomethyl)cyclopropane and sodium hydride, to give the compound as a colorless oil (77%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579351B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-c19e3d86b62b4fcd9ff51820b0e1b7a6 |
| Source note | uspto-grants-2009_08 |