HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 16678615, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-Fluorobenzyl bromide | HCID 68007 | — |
| Reactant | 8-(1-isopropylpiperidin-4-yloxy)-3,4-dihydropyrazino[1,2-a]indol-1(2H)-one | HCID 16679518 | — |
| Product | HCID 16678615 | HCID 16678615 | 79% |
Reaction Steps
The title compound was synthesized in analogy to example 17, from 8-(1-isopropyl-piperidin-4-yloxy)-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (example 1), sodium hydride and 3-fluorobenzyl bromide, to give the desired product as a white solid (79%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579351B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-48f161f52e9b4b86b2fc0fc5187eca3b |
| Source note | uspto-grants-2009_08 |