HCID 178526762, compound → HCID 178507989, compound

HRID 2105452Notes

Reaction equation

HRID 2105452 reaction equation
[N+:1]([C:4]1[CH:5]=[N:6][C:7]2[C:12]([C:13]=1[OH:14])=[N:11][CH:10]=[CH:9][CH:8]=2)([O-])=O.[N+:15]([C:18]1[CH:19]=[N:20][C:21]2[C:26]([C:27]=1[OH:28])=[CH:25][CH:24]=[CH:23][CH:22]=2)([O-])=O>>[NH2:1][C:4]1[CH:5]=[N:6][C:7]2[C:12]([C:13]=1[OH:14])=[N:11][CH:10]=[CH:9][CH:8]=2.[NH2:15][C:18]1[CH:19]=[N:20][C:21]2[C:26]([C:27]=1[OH:28])=[CH:25][CH:24]=[CH:23][CH:22]=2

Participants

4

Reactant 2

HCID 178526762HCID 178526762, compoundHCID 178526774HCID 178526774, compound

Product 2

HCID 178507989HCID 178507989, compoundHCID 178508000HCID 178508000, compound

Procedure

In step (4) of Reaction Scheme II, a 3-nitro[1,5]naphthyridin-4-ol or 3-nitroquinolin-4-ol of Formula XXIX is reduced to provide a 3-amino[1,5]naphthyridin-4-ol or 3-aminoquinolin-4-ol of Formula XXX. The reduction can be carried out using the methods described in step (1) of Reaction Scheme I.

Workup

  1. customIn step (4) of Reaction Scheme II

Sources & evidence

ORD record
ord-4b77e0217f3243639df026afeb78b87c
Source dataset
uspto-grants-2009_08
Patent number
US07579359B2

Reaction notes

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