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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 210548Generated: October 30, 2026

Diethyl Ether → 1-[2,5-Dimethyl-4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]-2-[4-[4-nitro-3-(trifluoromethyl)anilino]cyclohexyl]oxyethanone

https://huagongshe.com/reaction/210548

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantDimethylformamideHCID 6228—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantNpc316347HCID 3280088—
Reactant4-(4-Nitro-3-trifluoromethyl-phenylamino)-cyclohexanolHCID 43386224—
Reactant2-Chloro-1-[2,5-dimethyl-4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]ethanoneHCID 66852173—
Product1-[2,5-Dimethyl-4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]-2-[4-[4-nitro-3-(trifluoromethyl)anilino]cyclohexyl]oxyethanoneHCID 44194127—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-6e13eab0fd944d7e8e72e33bc033b38c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)