HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Methylhydroxylamine hydrochloride → HCID 67505835, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Methylhydroxylamine hydrochloride | HCID 521874 | — |
| Reactant | O-(propan-2-yl)hydroxylamine hydrochloride | HCID 12696235 | — |
| Reactant | HCID 66765094 | HCID 66765094 | — |
| Product | HCID 67505835 | HCID 67505835 | 72.7% |
Reaction Steps
The method of Part B of Example 25 was followed using O-isopropylhydroxylamine hydrochloride (2.4 g, 21 mmol) in lieu of O-methylhydroxylamine hydrochloride to treat N-(4-chloroquinolin-3-yl)pentanamide (4.5 g, 17 mmol) with the modification that the reaction was heated at reflux overnight. 2-Butyl-1-isopropoxy-1H-imidazo[4,5-c]quinoline (3.5 g) was obtained as a dark oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579359B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-e26759ff422c45c38c478bb242801630 |
| Source note | uspto-grants-2009_08 |