HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-3-methylbutane → [1-(3-Methyl-butyl)-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-3-methylbutane | HCID 7891 | — |
| Reactant | Methyl 2-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)acetate | HCID 21519358 | — |
| Product | [1-(3-Methyl-butyl)-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]-acetic acid methyl ester | HCID 69003096 | — |
Reaction Steps
Following a similar N-alkylation procedure described in example 9, the (2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl)-acetic acid methyl ester (0.068 mmol) obtained in the previous step is alkylated with 1-bromo-3-methylbutane to give the crude [1-(3-methyl-butyl)-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]-acetic acid methyl ester, which is used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579363B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-833df7691f224511bae6ad23026ea0ba |
| Source note | uspto-grants-2009_08 |