HCID 59648645, compound → HCID 59648655, compound

Participants

Reaction Steps

To a solution of 4-phenylethynyl-furan-2-carbaldehyde (1.54 g, 7.84 mmol) in MeOH was added palladium on carbon (Pd/C) (154 mg, 10% Pd by weight). A vacuum was applied to the reaction mixture and back filled with H2 4 times. The reaction was then allowed to stir at rt for 14 h under an atmosphere of H2 before being filtered through a plug of Celite® with EtOAc. The reaction was then concentrated in vacuo to give 4-phenethyl-furan-2-carbaldehyde as a colorless oil (1.53 g, 97%). 1H NMR (400 MHz, CDCl3) δ ppm 9.59 (d, J=0.6 Hz, 1 H) 7.40 (d, J=0.8 Hz, 1 H) 7.28-7.34 (m, 2 H) 7.20-7.26 (m, 1 H) 7.14-7.20 (m, 2 H) 7.05 (d, J=0.6 Hz, 1 H) 2.87-2.94 (m, 2 H) 2.78-2.85 (m, 2 H).

Provenance & Evidence