HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10702137, compound → (2E)-3-[6-(tert-Butyl)(3-pyridyl)]-N-[2-(hydroxymethyl)indol-5-yl]prop-2-enamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10702137 | HCID 10702137 | — |
| Reactant | HCID 50999229 | HCID 50999229 | — |
| Product | (2E)-3-[6-(tert-Butyl)(3-pyridyl)]-N-[2-(hydroxymethyl)indol-5-yl]prop-2-enamide | HCID 10286812 | — |
Reaction Steps
Analogous to the procedure used to prepare Example 1, (2E)-3-[6-(tert-butyl)(3-pyridyl)]prop-2-enoic acid, Example 44(b), (41 mg, 0.20 mmol) and (5-aminoindol-2-yl)methan-1-ol, Example 74(b), (32 mg, 0.20 mmol) provided, after purification by silica gel chromatography (20:80 hexane:EtOAc), the title compound as a yellow amorphous solid. MS (ESI, pos. ion) m/z: 350 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579347B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-2e1383f2c07d471ba49c2689a0320829 |
| Source note | uspto-grants-2009_08 |