化工社化工社 化学情報印刷レポート · 研究参考用
Dabco → 1-(4-{4-[3-[3-(4-Fluorophenyl)-3-hydroxypropyl]-2-(4-methoxyphenyl)-4-oxoazetidin-1-yl]-phenoxymethyl}-benzyl)-4-aza-1-azoniabicyclo[2.2.2]octane bromide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dabco | HCID 9237 | — |
| 反応物 | 1-[4-(4-Bromomethylbenzyloxy)-phenyl]-3-[3-(4-fluorophenyl)-3-hydroxypropyl]4-(4-methoxyphenyl)-azetidin-2-one | HCID 21083167 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 1-(4-{4-[3-[3-(4-Fluorophenyl)-3-hydroxypropyl]-2-(4-methoxyphenyl)-4-oxoazetidin-1-yl]-phenoxymethyl}-benzyl)-4-aza-1-azoniabicyclo[2.2.2]octane bromide | HCID 21083163 | — |
反応手順
Compound (25) and DABCO were dissolved in toluene and reacted analogously to Example IV, giving the product (26) as a colorless solid of molecular weight 716.70 (C39H43BrFN3O4); MS (ESI): 636.3 (MH+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07579339B2 |
| 出典データセット | uspto-grants-2009_08 |
| ORD ID | ord-a0c4a659c15a4886a2686d4f6966de97 |
| 出典メモ | uspto-grants-2009_08 |