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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105801Generated: October 30, 2026

Methyl acetoacetate → HCID 58999136, compound

https://huagongshe.com/reaction/2105801

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl acetoacetateHCID 7757—
Reactant1-AminopiperidineHCID 16658—
ReactantCyclopropanemethanamineHCID 75646—
Reactant2-Bromo-1-[4-(trifluoromethoxy)phenyl]ethan-1-oneHCID 2778691—
ProductHCID 58999136HCID 58999136—

Reaction Steps

The title compound was synthesized in analogy to Example 68, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-(4-trifluoromethoxy-phenyl)-ethanone as compound of formula S, cyclopropanemethylamine as R3-(CH2)m-NH2 and 1-piperidinamine as R1R2NH, MS (ISP) 422.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579369B2
Source datasetuspto-grants-2009_08
ORD IDord-55882b0a9891492da20da3493773af70
Source noteuspto-grants-2009_08