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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105806Generated: November 3, 2026

Methyl acetoacetate → HCID 58998959, compound

https://huagongshe.com/reaction/2105806

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl acetoacetateHCID 7757—
ReactantCyclohexylamineHCID 7965—
ReactantCyclopropanemethanamineHCID 75646—
ReactantHCID 2778779HCID 2778779—
ProductHCID 58998959HCID 58998959—

Reaction Steps

The title compound was synthesized in analogy to Example 68, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-(2-fluoro-3-trifluoromethyl-phenyl)-ethanone as compound of formula S, cyclopropanemethylamine as R3—(CH2)m—NH2 and cyclohexylamine as R1R2NH, MS (ISP) 423.4 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579369B2
Source datasetuspto-grants-2009_08
ORD IDord-8721469858d242deb2163f44c13c0215
Source noteuspto-grants-2009_08