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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105807Generated: November 1, 2026

Methyl acetoacetate → HCID 58999082, compound

https://huagongshe.com/reaction/2105807

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl acetoacetateHCID 7757—
Reactant1-AminopiperidineHCID 16658—
ReactantCyclopropanemethanamineHCID 75646—
ReactantHCID 2778779HCID 2778779—
ProductHCID 58999082HCID 58999082—

Reaction Steps

The title compound was synthesized in analogy to Example 68, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-(2-fluoro-3-trifluoromethyl-phenyl)-ethanone as compound of formula S, cyclopropanemethylamine as R3—(CH2)m—NH2 and 1-piperidinamine as R1R2NH, MS (ISP) 424.4 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579369B2
Source datasetuspto-grants-2009_08
ORD IDord-5f079594e3e34496a388fead949585f7
Source noteuspto-grants-2009_08