HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-methyl-5-(trifluoromethyl)benzoyl Chloride → 1-[2-Methyl-5-(trifluoromethyl)phenyl]ethan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-methyl-5-(trifluoromethyl)benzoyl Chloride | HCID 2775604 | — |
| Reactant | HCID 178418573 | HCID 178418573 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-[2-Methyl-5-(trifluoromethyl)phenyl]ethan-1-one | HCID 46737522 | — |
Reaction Steps
The title compound was synthesized from 2-methyl-5-(trifluoromethyl)-benzoyl chloride via the reaction of the corresponding Weinreb amide with methyl magnesium bromide in THF.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579369B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-dc1da811360c4c8ca6f7f74f693c1c31 |
| Source note | uspto-grants-2009_08 |