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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105864Generated: October 25, 2026

Tert-Butylamine → N-(tert-butyl)-2-piperazin-1-ylacetamide

https://huagongshe.com/reaction/2105864

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-ButylamineHCID 6385—
ReactantChloroacetyl chlorideHCID 6577—
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
ProductN-(tert-butyl)-2-piperazin-1-ylacetamideHCID 2468184—

Reaction Steps

The title compound was prepared from 1-tert-butyloxycarbonyl-piperazine, chloroacetyl-chloride and N-tert-butylamine in an analogous manner as described in example 21.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579368B2
Source datasetuspto-grants-2009_08
ORD IDord-654eb650546a4a93b4d1d91ca073fbf6
Source noteuspto-grants-2009_08