Chloroacetyl chloride → HCID 57809171, compound

HRID 2105865Notes

Reaction equation

C(O[C:6]([N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=O)(C)(C)C.ClC[C:16](Cl)=[O:17].[C:19]([CH2:21][NH:22][CH3:23])#[N:20]>>[C:19]([CH2:21][N:22]([CH3:23])[C:16](=[O:17])[CH2:6][N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1)#[N:20]

Participants

Reactant 3

HCID 6577Chloroacetyl chloride

HCID 36652Acetonitrile, 2-(methylamino)-

HCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 57809171HCID 57809171, compound

Procedure

The title compound was prepared from 1-tert-butyloxycarbonyl-piperazine, chloroacetylchloride and N-cyanomethyl-N-methylamine in an analogous manner as described in example 21.

Sources & evidence

ORD record: ord-0241ece316744810bc1ca3c04e4de3ec
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07579368B2

Reaction notes

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