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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105866Generated: October 31, 2026

Chloroacetyl chloride → 1-(2-oxo-2-piperidin-1-ylethyl)piperazine

https://huagongshe.com/reaction/2105866

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroacetyl chlorideHCID 6577—
ReactantPiperidineHCID 8082—
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
Product1-(2-oxo-2-piperidin-1-ylethyl)piperazineHCID 2760439—

Reaction Steps

The title compound was prepared from 1-tert-butyloxycarbonyl-piperazine, chloroacetylchloride and piperidine in an analogous manner as described in example 21.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579368B2
Source datasetuspto-grants-2009_08
ORD IDord-0c5be6d909f24dd0a61eb911277eedb3
Source noteuspto-grants-2009_08